Dieter Manstein, M.D., Ph.D

• Dieter Manstein, M.D., Ph.D

  Co-Inventor of Fractional Photothermolysis (Fraxel) together with Dr. Rox Anderson of Harvard Medical School
  
• Inventor of Selective Cryolipolysis for Body Contouring (developed by the Coolsculpting by Zeltiq™ company)
  
• First Recipient of the Furumoto’s Scientific Innovator Award of the American Society for Laser Medicine and Surgery

Residency Training in Dermatology
University of Munster, Germany

Ph.D. in Physics/Lasers
University of Munster, Germany

Fellowship in Clinical Applications of Lasers
Harvard Medical School Wellman Center for Photomedicine

Clinical Instructor
Massachusetts General Hospital Department of Dermatology / Harvard Medical School (2004-Present)
Fluent in Spanish and German

Doctor Dieter Manstein’s published articles

• Effects of non-invasive, 1,210 nm laser exposure on adipose tissue: Results of a human pilot study.
  Wanner M, Avram M, Gagnon D, Mihm MC Jr, Zurakowski D, Watanabe K, Tannous Z, Anderson RR, Manstein D.
  Lasers Surg Med. 2009 Jul 8;41(6):401-407. [Epub ahead of print]
  PMID: 19588533 [PubMed - as supplied by publisher]
  

• Thermal Injury Causes DNA Damage and Lethality in Unheated Surrounding Cells: Active Thermal Bystander Effect.
  Purschke M, Laubach HJ, Anderson RR, Manstein D.
  J Invest Dermatol. 2009 Jul 9. [Epub ahead of print]
  PMID: 19587691 [PubMed - as supplied by publisher]

• The effects of multiple passes on the epidermal thermal damage pattern in nonablative fractional resurfacing.
  Manstein D, Zurakowski D, Thongsima S, Laubach H, Chan HH.
  Lasers Surg Med. 2009 Feb;41(2):149-53.
  PMID: 19226571 [PubMed - in process]

• Effects of a 1,450 nm diode laser on facial sebum excretion.
  Laubach HJ, Astner S, Watanabe K, Clifford J, Rius-Diaz F, Zurakowski D, Manstein D.
  Lasers Surg Med. 2009 Feb;41(2):110-5.
  PMID: 19226569 [PubMed - in process]

• Selective cryolysis: a novel method of non-invasive fat removal.
  Manstein D, Laubach H, Watanabe K, Farinelli W, Zurakowski D, Anderson RR.
  Lasers Surg Med. 2008 Nov;40(9):595-604.
  PMID: 18951424 [PubMed - indexed for MEDLINE]

• Intense focused ultrasound: evaluation of a new treatment modality for precise microcoagulation within the skin.
  Laubach HJ, Makin IR, Barthe PG, Slayton MH, Manstein D.
  Dermatol Surg. 2008 May;34(5):727-34.
  PMID: 18429926 [PubMed - indexed for MEDLINE]

• The prevalence and risk factors of post-inflammatory hyperpigmentation after fractional resurfacing in Asians.
  Chan HH, Manstein D, Yu CS, Shek S, Kono T, Wei WI.
  Lasers Surg Med. 2007 Jun;39(5):381-5.
  PMID: 17518354 [PubMed - indexed for MEDLINE]

• Prospective direct comparison study of fractional resurfacing using different fluences and densities for skin rejuvenation in Asians.
  Kono T, Chan HH, Groff WF, Manstein D, Sakurai H, Takeuchi M, Yamaki T, Soejima K, Nozaki M.
  Lasers Surg Med. 2007 Apr;39(4):311-4.
  PMID: 17457835 [PubMed - indexed for MEDLINE]

• [Fractional photothermolysis]
  Laubach HJ, Manstein D.
  Hautarzt. 2007 Mar;58(3):216-8, 220-3. Review. German.
  PMID: 17318467 [PubMed - indexed for MEDLINE]

• Effects of skin temperature on lesion size in fractional photothermolysis.
  Laubach H, Chan HH, Rius F, Anderson RR, Manstein D.
  Lasers Surg Med. 2007 Jan;39(1):14-8.
  PMID: 17252573 [PubMed - indexed for MEDLINE]

• Selective photothermolysis of lipid-rich tissues: a free electron laser study.
  Anderson RR, Farinelli W, Laubach H, Manstein D, Yaroslavsky AN, Gubeli J 3rd, Jordan K, Neil GR, Shinn M, Chandler W, Williams GP, Benson SV, Douglas DR, Dylla HF.
  Lasers Surg Med. 2006 Dec;38(10):913-9.
  PMID: 17163478 [PubMed - indexed for MEDLINE]

• Complications of laser dermatologic surgery.
  Willey A, Anderson RR, Azpiazu JL, Bakus AD, Barlow RJ, Dover JS, Garden JM, Kilmer SL, Landa N, Manstein D, Ross EV Jr, Sadick N, Tanghetti EA, Yaghmai D, Zelickson BD.
  Lasers Surg Med. 2006 Jan;38(1):1-15.
  PMID: 16444692 [PubMed - indexed for MEDLINE]

• Skin responses to fractional photothermolysis.
  Laubach HJ, Tannous Z, Anderson RR, Manstein D.
  Lasers Surg Med. 2006 Feb;38(2):142-9.
  PMID: 16392146 [PubMed - indexed for MEDLINE]

• Q-switched ruby versus long-pulsed dye laser delivered with compression for treatment of facial lentigines in Asians.
  Kono T, Manstein D, Chan HH, Nozaki M, Anderson RR.
  Lasers Surg Med. 2006 Feb;38(2):94-7.
  PMID: 16265659 [PubMed - indexed for MEDLINE]

• Intradermally focused infrared laser pulses: thermal effects at defined tissue depths.
  Khan MH, Sink RK, Manstein D, Eimerl D, Anderson RR.
  Lasers Surg Med. 2005 Apr;36(4):270-80.
  PMID: 15719420 [PubMed - indexed for MEDLINE]

• Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury.
  Manstein D, Herron GS, Sink RK, Tanner H, Anderson RR.
  Lasers Surg Med. 2004;34(5):426-38.
  PMID: 15216537 [PubMed - indexed for MEDLINE]

• Extended theory of selective photothermolysis.
  Altshuler GB, Anderson RR, Manstein D, Zenzie HH, Smirnov MZ.
  Lasers Surg Med. 2001;29(5):416-32.
  PMID: 11891730 [PubMed - indexed for MEDLINE]